Mutation Rate Browser

The Mutation Rate Browser lets you explore patterns of fine-scale variability in human germline mutation rates.

Visualizing rates

We have created a preconfigured UCSC Genome Browser track for visualizing these rates alongside other genomic data.

Download the data

The raw data used to create these tracks can be downloaded at Tracks are only available for assembly GRCh37 (hg19) of the human reference genome, but can be converted to coordinates in other assemblies using the UCSC liftOver utility. Tracks are in a compressed wiggle (BigWig) format. Because these files are quite large (~50GB total), we recommend using a download manager such as wget or curl.


Carlson, J. et al. Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans. Nat. Commun. 9, 3753 (2018). doi:10.1038/s41467-018-05936-5


Mr. Eel is a lightweight tool we designed to quickly annotate a list of single-nucleotide variants with their estimated mutation rates.

This utility presently annotates using only the 7-mer sequence context, not accounting for local genomic features as implemented in the Genome Browser tracks above (though this feature is under development).


Jedidiah Carlson (Twitter/GitHub).

Jedidiah Carlson


MIT License